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Saturday, February 2, 2008

human genome sequence assembly

The NCBI Map Viewer provides graphical displays of features on the human genome sequence assembly as well as cytogenetic, genetic, physical, and radiation hybrid maps. Extensive documentation is provided to describe the resource features and methods used, tutorials, and statistics.

Map features that can be seen along the sequence include genes, transcripts, NCBI contigs (the 'Contig' map), the BAC tiling path (the 'Component' map), STSs, FISH mapped clones, ESTs and transcripts from several different organisms, Gnomon predicted gene models, and more.

You can find genes or markers of interest by submitting a query against the whole genome, or a chromosome at a time. Use the Advanced Search form for more complex queries. Results are indicated both graphically, as tick marks on the ideogram, and in a tabular format. The results table includes links to a chromosome graphical view where the gene or marker can be seen in the context of additional data. For genes, a particularly useful display includes the Gene, Ab initio (e.g., the Gnomon predicted models), and UniGene sequence maps. You can also browse a chromosome by clicking on a chromosome link in the ideogram above. Use the "Maps & Options" window, available on individual chromosome displays, to configure your display.

Please note that other genomes can also be viewed in the NCBI Map Viewer resource. The Map Viewer Home Page provides a current list. Additional organism-specific web pages are listed on the Genomic Biology site.

http://www.ncbi.nlm.nih.gov/mapview/map_search.cgi?taxid=9606

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